Welcome to the CSLB
The Centre for Speech, Language and the Brain, headed by Professor Lorraine K Tyler, is part of the Department of Psychology at the University of Cambridge. Our interdisciplinary research covers a wide range of issues in the cognitive neuroscience of language, object processing, semantics, the ageing brain and cognition. We integrate behavioural experimental and neuroimaging studies on healthy people, together with similar research on brain-damaged patients.
The CSLB welcomes applications from postgraduate students for 2014 entry.
Given the interdisciplinary nature of our research, we particularly welcome applicants with a background in scientific computing, statistics, machine learning and/or signal processing methods. For more information click here.
News from the CSLB
- 2 Dec 2013
New publication in Journal of Neuroscience:
Dr Barry Devereux, Professor Lorraine K. Tyler and colleagues used Representational Similarity Analysis (RSA) to investigate the commonalities and differences in the semantic processing of words and objects. The results showed that some regions are invariant in word and object processing: activation patterns were similar for objects and words. However, other regions show different activation patterns depending on whether words or objects were viewed. These findings have important consequences for research into how people process meaning, by showing that merely identifying the regions involved in both word and picture processing is not sufficient evidence that they form part of a common semantic network.
Dr Devereux has summarised his research for the layperson here. You can also check out the journal website or full article as a PDF.
- 25 July 2013
The BBSRC have released five short promotional films about the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) - a pan-Cambridge project on healthy ageing, funded by the BBSRC, that brings together the University of Cambridge Departments of Psychology, Psychiatry, Engineering and Public Health, the MRC Cognition and Brain Sciences Unit, and the MRC Biostatistics Unit. This project includes detailed cognitive and neuroimaging profiling of 700 people from 18-88 years of age, and is led by Professor Lorraine K Tyler.
Professor Rik Henson, one of the MRC CBU Co-Investigators, comments: "Although the 5-year project is only half-way through, and the results not yet fully analysed, the aims and scope of the project are well captured by these engaging vignettes."
The videos can be found here:
- Part #1: Cam-CAN project overview
- Part #2: MRI brain imaging
- Part #3: MEG brain waves
- Part #4: Motor learning experiment
- Part #5: Hitchcock emotional movie response
Further details of the Cam-CAN project can be found at www.cam-can.com.
- 3 Jul 2013
Lorraine K Tyler and colleagues have published a new paper using, for the first time, representational similarity analysis on MEG data obtained on spoken sentences, to characterize the syntactic computations performed by regions within the fronto-temporal language system. Testing a variety of lexico-syntactic and ambiguity models against the MEG data, the results differentiate the computations carried within the L MTG and LIFG in syntactic processing; the L MTG represents and transmits lexical information to the LIFG, which responds to and resolves syntactic ambiguity. The paper is published in Frontiers in Psychology.
- 10 May 2013
New publication in Journal of Cognitive Neuroscience available via Early Access:
Professor Lorraine K Tyler, Dr Kirsten Taylor and colleagues investigated how the brain's responses during object (picture) naming were modulated by the statistical properties of the object's semantic features. These findings help to integrate previously disparate findings by suggesting that both object-specific and category representations can be explained in terms of a critical interaction: the computational properties of different neural regions within the ventral stream with the semantic features of objects.
Click for our neurocognitive account of conceptual knowledge, the journal website or local PDF.
- More ...
Major themes cross-cutting our research
Neurobiology of spoken language in healthy and brain-damaged populations:
- Working with healthy people, we develop accounts of the functional relationships between the anatomically distributed regions involved in language processing.
- Working with brain-damaged patients (in both the acute and chronic phases), we investigate issues of reorganisation and plasticity following brain damage.
Neurocognitive accounts of conceptual knowledge:
- How is meaning represented and processed in the mind and brain? We develop cognitive models of conceptual knowledge and investigate how conceptual knowledge is processed in both the healthy and damaged system.
The ageing brain and cognition:
- We study language function in normal healthy ageing to determine the relationship between preserved function and neural change.
Major new study in brain ageing (Cam-CAN)
Research efforts to understand how the brain changes with age, from early to late adulthood, have been given a major boost by a new £5M grant from the BBSRC. The funding has been awarded to a team of scientists from the University of Cambridge Departments of Psychology, Public Health, Psychiatry, Clinical Neurosciences and Engineering, and from the MRC Cognition and Brain Sciences Unit. This team, working as the Cambridge Centre for Ageing and Neuroscience (Cam-CAN), brings together world-leading expertise and cutting edge methods to understand how brain ageing in healthy people affects abilities like language, attention, emotion and memory.
The ageing process does not have a uniform effect across the brain. Older people often struggle, for example, to recall the right word in a conversation, but can continue to expand their vocabulary throughout old age. Understanding what structures in the brain account for this variation will be a crucial first step in allowing more people to retain a range of mental abilities throughout their lives. Professor Lorraine K Tyler, who heads the research team, said "Our mental abilities don't suddenly start to decline as we enter retirement. In fact, many are retained right into our eighties and we are often too quick to attribute normal lapses like forgetfulness to the effects of age. Understanding the complexities of how ageing affects the brain will be crucial for older people to be able to live fulfilled lives and contribute fully to society."
The study is unique in recruiting 3000 people aged 18-88 years, drawn from the general population, to create a library of information on how healthy brain ageing affects mental abilities to different degrees. Not only will this help identify older people who might be helped by therapies, but will also provide a lasting resource for future researchers to draw on. The research will establish a virtual "brain and behaviour" database which will hold behavioural, MRI and MEG data from a population-representative sample of 700 healthy adults. This will be a valuable, open-access resource for scientists interested in ageing, and a basis for longitudinal study of how our brain and our cognitive abilities change as we grow older.
ERC Advanced Investigator grant
An ERC Advanced Investigator Grant has been awarded to Professor Lorraine K Tyler. This 5-year programme will support her research programme 'PERCEPCON', investigating how the brain processes visual inputs as meaningful objects.
More about us
The Centre is directed by Professor Lorraine K Tyler, Professor of Cognitive Neuroscience and Fellow of Clare College. Researchers at the CSLB come from various academic fields such as cognitive psychology, neuroscience, linguistics, cognitive science, and computer science. We collaborate with scientists at the Department of Psychiatry, the Department of Clinical Neurosciences, the Behavioural and Clinical Neuroscience Institute, the MRC Cognition and Brain Sciences Unit, the Wolfson Brain Imaging Centre, Johns Hopkins University, Pomona College, and University Hospital Basel.
The Centre, formerly called the Centre for Speech and Language, is/has recently been funded by grants from
- Medical Research Council (MRC)
- Biotechnology and Biological Sciences Research Council(BBSRC) Strategic Longer and Larger Grant
- European Research Council Advanced Investigator Grant
- Dunhill Medical Trust
- Engineering and Physical Sciences Research Council (EPSRC)
- Isaac Newton Trust
- Research into Ageing
- British Academy
- EC FP6 Marie Curie Fellowship
- Economic and Social Research Council (ESRC)